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Q1 LONG ANSWER 10M ★ High-yield

Describe the plans A, B, C of Acute Diarrhoea — Assessment of Dehydration & WHO Management.

Pediatrics · Final Professional

Definition

  • Diarrhoea is the passage of 3 or more loose or watery stools in a 24-hour period (or a change from the normal pattern that the mother considers abnormal).
  • Acute diarrhoea lasts < 14 days.
  • It is a leading cause of under-5 mortality in India, chiefly through dehydration and its consequences.

Etiology

  • Viral (commonest): Rotavirus (the leading cause of severe dehydrating diarrhoea in infants), norovirus, adenovirus.
  • Bacterial: enterotoxigenic E. Coli (ETEC), Shigella (dysentery), Vibrio cholerae (rice-water stools), Salmonella, Campylobacter.
  • Parasitic: Giardia lamblia, Entamoeba histolytica, Cryptosporidium.
  • Non-infective: antibiotic-associated, feeding errors, food allergy, malabsorption.

Pathophysiology (mechanisms)

  • Secretory — enterotoxins (e.g. Cholera toxin) activate cAMP → active Cl⁻ and water secretion → voluminous watery stools that persist with fasting.
  • Osmotic — unabsorbed solutes (e.g. Lactose in disaccharidase deficiency) draw water into the lumen; stops with fasting.
  • Invasive/inflammatory — mucosal invasion (Shigella, Entamoeba) → blood, mucus and pus in stool (dysentery).

Assessment of Dehydration (WHO)

The single most important step is to assess the degree of dehydration, which then guides the treatment plan:

SignNo dehydrationSome dehydrationSevere dehydration
General conditionWell, alertRestless, irritableLethargic / unconscious
EyesNormalSunkenVery sunken & dry
ThirstDrinks normallyThirsty, drinks eagerlyDrinks poorly / unable
Skin pinchGoes back quicklyGoes back slowlyGoes back very slowly (> 2 s)
Fluid deficit< 5%5–10%> 10%
AgeFirst give 30 mL/kg inThen give 70 mL/kg in
< 12 months1 hour5 hours
≥ 12 months30 minutes2½ hours
  • Reassess every 15–30 min; if not improving, give fluids faster.
  • Start ORS (~5 mL/kg/hr) as soon as the child can drink; give zinc when feeding resumes.
  • If IV access is impossible → ORS by nasogastric tube (20 mL/kg/hr).

Complications

  • Dehydration → hypovolaemic shock, acute kidney injury, and death.
  • Electrolyte disturbances — hypo/hypernatraemia, hypokalaemia (ileus, weakness), acidosis.
  • Persistent diarrhoea; malnutrition; secondary lactose intolerance; seizures (dysnatraemias).

Prevention

  • Exclusive breastfeeding; safe complementary feeding; hand-washing and safe drinking water & sanitation.
  • Rotavirus vaccine and measles vaccine; vitamin A; use of ORS + zinc at community level.

Clinical Features

  • Frequent loose/watery stools with or without vomiting; the history should note the number, volume and character (watery vs bloody) of stools and vomits.
  • Features of dehydration — irritability or lethargy, sunken eyes, dry mouth, reduced urine output, thirst.
  • Fever, abdominal pain and, in dysentery, blood/mucus in the stool with tenesmus.
  • Signs of associated problems — malnutrition, respiratory infection, or systemic sepsis.

Investigations (usually Clinical; Tests Only If Indicated)

  • Most acute watery diarrhoea needs no investigation — assessment of hydration is clinical.
  • Stool examination (microscopy/culture) if the stool is bloody, in suspected cholera, in persistent diarrhoea, or in an immunocompromised child.
  • Serum electrolytes, blood glucose & renal function in severe dehydration, altered sensorium, convulsions, or before/during IV therapy.
  • Blood counts and a septic screen if systemic infection is suspected.

WHY You Must Never Stop Feeding

  • One of the most damaging traditional practices in India is understanding why withholding food from a child with diarrhoea — done with the best intentions, to 'rest the bowel' — is actively harmful and kills children.
  • It is intuitive to think that if food goes in and diarrhoea comes out, stopping the food will stop the diarrhoea.
  • But this is wrong on every count.
  • First, the absorptive capacity of the gut is largely preserved even in acute diarrhoea — 60–90% of nutrients continue to be absorbed.
  • Second, the gut mucosa depends on luminal nutrition to maintain itself: starving it causes villous atrophy, which impairs absorption further and prolongs the diarrhoea.
  • Third, and most importantly, the child is catabolic and is losing protein and nutrients — so a few days of starvation, repeated with each episode of diarrhoea (and Indian children may have several episodes a year), is precisely how acute diarrhoea converts a normally-nourished child into a malnourished one, and a malnourished child into a dead one.
  • Hence the rule: continue breastfeeding and feeding throughout, and give an extra meal a day for two weeks afterwards to catch up.

All questions in Fluids, Electrolytes & Diarrhoea

  1. Q1Describe the plans A, B, C of Acute Diarrhoea — Assessment of Dehydration & WHO Management. ★
  2. Q2Discuss Oral Rehydration Therapy (ORT) & ORS — its causes, clinical features and management. ★
  3. Q3Define Persistent Diarrhoea. Describe its pathophysiology, causes, investigations and management. ★
  4. Q4Define Fluid & Electrolyte Therapy in Children. Describe its types and management. ★
  5. Q5Describe the bloody Diarrhoea of Acute Dysentery. ★
  6. SN1Describe the by Serum Sodium of Types of Dehydration. ★
  7. SN2Write a short note on Zinc in Diarrhoea. ★
  8. SN3Define Cholera. Describe its pathogenesis, clinical features, management and prevention.
  9. SN4Define Complications of Acute Diarrhoea. Describe its prevention, clinical features and management.
  10. SN5Define Rotavirus & Diarrhoea Prevention. Describe its clinical features and treatment.
  11. SN6Define Hypernatraemic Dehydration. Describe its causes, pathophysiology, management and investigations.
  12. SN7Define Hypokalaemia in Children. Describe its causes, clinical features, management and prevention.

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