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Describe the plans A, B, C of Acute Diarrhoea — Assessment of Dehydration & WHO Management.
Definition
- Diarrhoea is the passage of 3 or more loose or watery stools in a 24-hour period (or a change from the normal pattern that the mother considers abnormal).
- Acute diarrhoea lasts < 14 days.
- It is a leading cause of under-5 mortality in India, chiefly through dehydration and its consequences.
Etiology
- Viral (commonest): Rotavirus (the leading cause of severe dehydrating diarrhoea in infants), norovirus, adenovirus.
- Bacterial: enterotoxigenic E. Coli (ETEC), Shigella (dysentery), Vibrio cholerae (rice-water stools), Salmonella, Campylobacter.
- Parasitic: Giardia lamblia, Entamoeba histolytica, Cryptosporidium.
- Non-infective: antibiotic-associated, feeding errors, food allergy, malabsorption.
Pathophysiology (mechanisms)
- Secretory — enterotoxins (e.g. Cholera toxin) activate cAMP → active Cl⁻ and water secretion → voluminous watery stools that persist with fasting.
- Osmotic — unabsorbed solutes (e.g. Lactose in disaccharidase deficiency) draw water into the lumen; stops with fasting.
- Invasive/inflammatory — mucosal invasion (Shigella, Entamoeba) → blood, mucus and pus in stool (dysentery).
Assessment of Dehydration (WHO)
The single most important step is to assess the degree of dehydration, which then guides the treatment plan:
| Sign | No dehydration | Some dehydration | Severe dehydration |
|---|---|---|---|
| General condition | Well, alert | Restless, irritable | Lethargic / unconscious |
| Eyes | Normal | Sunken | Very sunken & dry |
| Thirst | Drinks normally | Thirsty, drinks eagerly | Drinks poorly / unable |
| Skin pinch | Goes back quickly | Goes back slowly | Goes back very slowly (> 2 s) |
| Fluid deficit | < 5% | 5–10% | > 10% |
| Age | First give 30 mL/kg in | Then give 70 mL/kg in |
|---|---|---|
| < 12 months | 1 hour | 5 hours |
| ≥ 12 months | 30 minutes | 2½ hours |
- Reassess every 15–30 min; if not improving, give fluids faster.
- Start ORS (~5 mL/kg/hr) as soon as the child can drink; give zinc when feeding resumes.
- If IV access is impossible → ORS by nasogastric tube (20 mL/kg/hr).
Complications
- Dehydration → hypovolaemic shock, acute kidney injury, and death.
- Electrolyte disturbances — hypo/hypernatraemia, hypokalaemia (ileus, weakness), acidosis.
- Persistent diarrhoea; malnutrition; secondary lactose intolerance; seizures (dysnatraemias).
Prevention
- Exclusive breastfeeding; safe complementary feeding; hand-washing and safe drinking water & sanitation.
- Rotavirus vaccine and measles vaccine; vitamin A; use of ORS + zinc at community level.
Clinical Features
- Frequent loose/watery stools with or without vomiting; the history should note the number, volume and character (watery vs bloody) of stools and vomits.
- Features of dehydration — irritability or lethargy, sunken eyes, dry mouth, reduced urine output, thirst.
- Fever, abdominal pain and, in dysentery, blood/mucus in the stool with tenesmus.
- Signs of associated problems — malnutrition, respiratory infection, or systemic sepsis.
Investigations (usually Clinical; Tests Only If Indicated)
- Most acute watery diarrhoea needs no investigation — assessment of hydration is clinical.
- Stool examination (microscopy/culture) if the stool is bloody, in suspected cholera, in persistent diarrhoea, or in an immunocompromised child.
- Serum electrolytes, blood glucose & renal function in severe dehydration, altered sensorium, convulsions, or before/during IV therapy.
- Blood counts and a septic screen if systemic infection is suspected.
WHY You Must Never Stop Feeding
- One of the most damaging traditional practices in India is understanding why withholding food from a child with diarrhoea — done with the best intentions, to 'rest the bowel' — is actively harmful and kills children.
- It is intuitive to think that if food goes in and diarrhoea comes out, stopping the food will stop the diarrhoea.
- But this is wrong on every count.
- First, the absorptive capacity of the gut is largely preserved even in acute diarrhoea — 60–90% of nutrients continue to be absorbed.
- Second, the gut mucosa depends on luminal nutrition to maintain itself: starving it causes villous atrophy, which impairs absorption further and prolongs the diarrhoea.
- Third, and most importantly, the child is catabolic and is losing protein and nutrients — so a few days of starvation, repeated with each episode of diarrhoea (and Indian children may have several episodes a year), is precisely how acute diarrhoea converts a normally-nourished child into a malnourished one, and a malnourished child into a dead one.
- Hence the rule: continue breastfeeding and feeding throughout, and give an extra meal a day for two weeks afterwards to catch up.
All questions in Fluids, Electrolytes & Diarrhoea
- Q1Describe the plans A, B, C of Acute Diarrhoea — Assessment of Dehydration & WHO Management. ★
- Q2Discuss Oral Rehydration Therapy (ORT) & ORS — its causes, clinical features and management. ★
- Q3Define Persistent Diarrhoea. Describe its pathophysiology, causes, investigations and management. ★
- Q4Define Fluid & Electrolyte Therapy in Children. Describe its types and management. ★
- Q5Describe the bloody Diarrhoea of Acute Dysentery. ★
- SN1Describe the by Serum Sodium of Types of Dehydration. ★
- SN2Write a short note on Zinc in Diarrhoea. ★
- SN3Define Cholera. Describe its pathogenesis, clinical features, management and prevention.
- SN4Define Complications of Acute Diarrhoea. Describe its prevention, clinical features and management.
- SN5Define Rotavirus & Diarrhoea Prevention. Describe its clinical features and treatment.
- SN6Define Hypernatraemic Dehydration. Describe its causes, pathophysiology, management and investigations.
- SN7Define Hypokalaemia in Children. Describe its causes, clinical features, management and prevention.