SN3
SHORT NOTE
5M
★ High-yield
Define dietary fibre. Classify it and describe its physiological effects.
Definition
Dietary fibre = the indigestible portion of plant food, consisting of polysaccharides and lignin that resist digestion by human enzymes but may be fermented by colonic bacteria.
- Formerly called roughage and dismissed as inert; now recognised as nutritionally important
Classification
| Type | Components | Sources | Chief actions |
|---|---|---|---|
| Insoluble | Cellulose, hemicellulose, lignin | Wheat bran, whole grains, vegetables, fruit skins | Increases faecal bulk, shortens transit time, prevents constipation |
| Soluble | Pectin, gums, mucilage, β-glucan, inulin | Oats, barley, pulses, apple, guava, isabgol, guar | Lowers cholesterol and slows glucose absorption |
Physiological Effects
- Increases stool bulk and water content → softer stools, easier passage
- Shortens intestinal transit time → less contact between carcinogens and mucosa
- Binds bile acids → more cholesterol is diverted to bile acid synthesis → plasma cholesterol falls
- Slows gastric emptying and glucose absorption → a flatter post-prandial glucose curve and lower glycaemic index
- Increases satiety and lowers energy density → helps weight control
- Fermented by colonic bacteria to short-chain fatty acids — acetate, propionate and butyrate, which is the preferred fuel of the colonocyte
- Acts as a prebiotic, supporting a favourable gut microbiota
Recommended Intake
- 25–40 g/day in adults, or about 14 g per 1000 kcal
- The traditional Indian diet, rich in whole grains and pulses, is usually adequate; refined flour and polished rice reduce it sharply
Deficiency and Excess
| Low fibre intake | Excessive fibre intake |
|---|---|
| Constipation, haemorrhoids | Flatulence, bloating, abdominal discomfort |
| Diverticulosis | Binds and reduces absorption of iron, calcium and zinc (phytate) |
| Colorectal carcinoma (association) | May precipitate intestinal obstruction |
| Obesity, type 2 diabetes, dyslipidaemia | Reduced energy density in small children |
| Gallstones | Interferes with some drugs |
Applied Aspects
- Isabgol (psyllium husk) is a soluble fibre widely used in India as a bulk laxative and to lower cholesterol
- Fibre must be increased gradually and with adequate water, or it worsens constipation and causes bloating
- Phytate in bran binds iron, calcium and zinc, and can contribute to deficiency in populations already at risk — a genuine concern in Indian diets
- The evidence that fibre prevents colorectal cancer is weaker than once believed; its benefits for constipation, cholesterol and glycaemic control are firmly established
- Low-fibre diets are indicated in acute diverticulitis, inflammatory bowel disease flares and before colonoscopy
All questions in Cell, Biomolecules & Chemistry of Carbohydrates
- Q1Describe the structure and functions of the cell organelles. Give their marker enzymes and the principle of subcellular fractionation. ★
- Q2Describe the structure of the plasma membrane. Explain the mechanisms of transport across it. ★
- Q3Define and classify carbohydrates with suitable examples. Add a note on the derived carbohydrates. ★
- Q4Describe the isomerism shown by carbohydrates. Explain epimers, anomers and mutarotation with their significance. ★
- Q5Classify polysaccharides with examples. Compare starch, glycogen and cellulose. ★
- SN1Define reducing sugars. Describe the Benedict test and its clinical significance. ★
- SN2Describe the glycosidic bond with its types and significance. ★
- SN3Define dietary fibre. Classify it and describe its physiological effects. ★
- SN4Describe the structure and functions of lysosomes. Add a note on the lysosomal storage diseases. ★
- SN5Describe the structure and functions of glycoproteins. Add a note on the blood group antigens.
- SN6Describe the properties of water and the distribution of body water. ★
- SN7Define buffers. Describe the buffer systems of the body and the Henderson–Hasselbalch equation. ★