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Define dietary fibre. Classify it and describe its physiological effects.

Biochemistry · 1st Professional — Pre-Clinical

Definition

Dietary fibre = the indigestible portion of plant food, consisting of polysaccharides and lignin that resist digestion by human enzymes but may be fermented by colonic bacteria.

  • Formerly called roughage and dismissed as inert; now recognised as nutritionally important

Classification

TypeComponentsSourcesChief actions
InsolubleCellulose, hemicellulose, ligninWheat bran, whole grains, vegetables, fruit skinsIncreases faecal bulk, shortens transit time, prevents constipation
SolublePectin, gums, mucilage, β-glucan, inulinOats, barley, pulses, apple, guava, isabgol, guarLowers cholesterol and slows glucose absorption

Physiological Effects

  • Increases stool bulk and water content → softer stools, easier passage
  • Shortens intestinal transit time → less contact between carcinogens and mucosa
  • Binds bile acids → more cholesterol is diverted to bile acid synthesis → plasma cholesterol falls
  • Slows gastric emptying and glucose absorption → a flatter post-prandial glucose curve and lower glycaemic index
  • Increases satiety and lowers energy density → helps weight control
  • Fermented by colonic bacteria to short-chain fatty acids — acetate, propionate and butyrate, which is the preferred fuel of the colonocyte
  • Acts as a prebiotic, supporting a favourable gut microbiota

Recommended Intake

  • 25–40 g/day in adults, or about 14 g per 1000 kcal
  • The traditional Indian diet, rich in whole grains and pulses, is usually adequate; refined flour and polished rice reduce it sharply

Deficiency and Excess

Low fibre intakeExcessive fibre intake
Constipation, haemorrhoidsFlatulence, bloating, abdominal discomfort
DiverticulosisBinds and reduces absorption of iron, calcium and zinc (phytate)
Colorectal carcinoma (association)May precipitate intestinal obstruction
Obesity, type 2 diabetes, dyslipidaemiaReduced energy density in small children
GallstonesInterferes with some drugs

Applied Aspects

  • Isabgol (psyllium husk) is a soluble fibre widely used in India as a bulk laxative and to lower cholesterol
  • Fibre must be increased gradually and with adequate water, or it worsens constipation and causes bloating
  • Phytate in bran binds iron, calcium and zinc, and can contribute to deficiency in populations already at risk — a genuine concern in Indian diets
  • The evidence that fibre prevents colorectal cancer is weaker than once believed; its benefits for constipation, cholesterol and glycaemic control are firmly established
  • Low-fibre diets are indicated in acute diverticulitis, inflammatory bowel disease flares and before colonoscopy

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