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Classify errors of refraction and describe the mechanism of accommodation.

Physiology · 1st Professional — Pre-Clinical

Introduction

Errors of refraction occur when parallel rays of light are not brought to a focus on the retina with accommodation at rest.

  • The eye has a total refractive power of about 60 dioptres, of which the cornea contributes about 43 D (the largest single element) and the lens about 17 D at rest
  • The cornea contributes most because the difference in refractive index between air and cornea is greatest — which is why vision is blurred under water, where that difference disappears

Types of Refractive Error

ErrorDefectImage fallsCorrection
Myopia (short sight)Eyeball too long (axial) or refractive power too greatIN front of the retinaConcave (minus) lens
Hypermetropia (long sight)Eyeball too short or refractive power too weakBehind the retinaConvex (plus) lens
AstigmatismUnequal curvature in different meridia, usually cornealRays in different meridia focus at different points — no single point focusCylindrical lens
PresbyopiaAge-related loss of lens elasticity, so accommodation fails; not a true refractive errorNear objects cannot be focusedConvex lens for near work; begins around 40 years
AphakiaAbsence of the lensFar behind the retinaStrong convex lens or intraocular lens implant

CLINICAL PEARL

Presbyopia is not a refractive error and happens to everyone. The eye is optically normal; what fails is the lens’s ability to change shape, which declines steadily from childhood and crosses the threshold for comfortable reading at around 40. That is why it appears at much the same age worldwide, and why it needs a separate correction for near vision even in someone with perfect distance sight.

Accommodation

A near object is viewed → Impulses via the optic nerve to the edinger–westphal nucleus → Parasympathetic outflow in the oculomotor (III) nerve to the ciliary ganglion → ciliary muscle contracts → the suspensory ligament slackens → The elastic lens becomes more convex — power increases by up to about 14 D in a child → Accompanied by convergence of the eyes and pupillary constriction — the near reflex triad

  • Amplitude of accommodation falls with age — about 14 D at 10 years, 4 D at 40, and under 1 D by 60
  • Cycloplegic drugs paralyse the ciliary muscle and abolish accommodation, which is why they are used for accurate refraction in children, in whom active accommodation would otherwise mask hypermetropia

Applied Aspects

  • Uncorrected refractive error is the commonest cause of visual impairment worldwide, and one of the most easily and cheaply remediable — a pair of spectacles
  • School vision screening detects it at the age when it most affects learning, and is among the most cost-effective public health measures available
  • Myopia is rising sharply in urban Asian populations, and time spent outdoors in childhood appears protective; near work and indoor living are implicated
  • High myopia carries added risks — retinal detachment, myopic degeneration, glaucoma and early cataract; it is not merely an optical inconvenience
  • An adult who suddenly needs less reading correction may be developing nuclear cataract, which increases lens power and causes "second sight" — a useful and frequently missed clue
  • Sudden change in refraction can indicate diabetes, as osmotic swelling of the lens alters its power; blood glucose should be checked before prescribing new spectacles
  • Refraction in children must be done under cycloplegia, since their powerful accommodation conceals hypermetropia and produces a falsely low reading
  • Uncorrected error in one eye during childhood causes amblyopia, which becomes irreversible after the critical period — another reason early screening matters
  • Refractive surgery reshapes the cornea and is effective in suitable candidates, but does not remove the retinal risks of high myopia, which persist for life

All questions in Special Senses

  1. Q1Describe the refractive media of the eye and the mechanism of accommodation. Discuss the errors of refraction and their correction. ★
  2. Q2Compare rods and cones. Describe the mechanism of phototransduction and dark adaptation. ★
  3. Q3Trace the visual pathway. Describe the effects of lesions at different sites and the pupillary light reflex. ★
  4. Q4Describe the mechanism of hearing. Explain impedance matching, the transduction by hair cells and the analysis of pitch. ★
  5. Q5Describe the vestibular apparatus and its role in the maintenance of equilibrium. Add a note on nystagmus and the caloric test. ★
  6. SN1Describe the physiological basis of colour vision. Classify colour blindness and describe its inheritance. ★
  7. SN2Describe the formation, circulation and functions of aqueous humour. Add a note on glaucoma. ★
  8. SN3Classify deafness. Describe the tuning fork tests and their interpretation. ★
  9. SN4Describe the modalities of taste, the taste buds and the nerve supply of the tongue.
  10. SN5Describe the mechanism of olfaction and the olfactory pathway. Add a note on anosmia.
  11. SN6Describe the formation, circulation and functions of aqueous humour and the factors affecting intraocular pressure. ★
  12. SN7Classify errors of refraction and describe the mechanism of accommodation. ★

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