Q5
LONG ANSWER
10M
★ High-yield
Describe the normal electrocardiogram. Explain the leads, waves and intervals with their normal values, and give the uses of the ECG.
Definition
Electrocardiogram (ECG) = the graphic record of the electrical activity of the heart as recorded from the body surface.
- Recorded at a paper speed of 25 mm/s and a sensitivity of 1 mV = 10 mm
- Therefore 1 small square = 0.04 s and 1 large square = 0.2 s
Leads
| Group | Leads | Type |
|---|---|---|
| Bipolar limb (Einthoven) | I, II, III | Record potential difference between two limbs |
| Augmented unipolar limb | AVR, aVL, aVF | One limb vs an indifferent electrode |
| Unipolar chest (precordial) | V1–V6 | Chest wall vs Wilson central terminal |
- Lead I = left arm − right arm; Lead II = left leg − right arm; Lead III = left leg − left arm
- Einthoven's law — Lead II = Lead I + Lead III
- AVR is normally negative in all its deflections
Regional correlation
| Leads | Region of heart | Artery |
|---|---|---|
| II, III, aVF | Inferior | Right coronary |
| I, aVL, V5, V6 | Lateral | Left circumflex |
| V1–V4 | Anterior / septal | Left anterior descending |
Waves and Intervals
| Wave / interval | Represents | Normal duration | Normal amplitude |
|---|---|---|---|
| P wave | Atrial depolarisation | 0.08–0.10 s | < 2.5 mm |
| PR interval | Atrial depolarisation + AV nodal delay | 0.12–0.20 s | — |
| QRS complex | Ventricular depolarisation | 0.08–0.10 s | — |
| ST segment | Plateau — ventricles fully depolarised | 0.08 s | Isoelectric |
| T wave | Ventricular repolarisation | 0.2 s | — |
| QT interval | Total ventricular electrical activity | 0.40 s | — |
- Atrial repolarisation is not seen — it is buried within the QRS complex
- T wave is upright although it is repolarisation, because repolarisation proceeds from epicardium to endocardium, the reverse of depolarisation
Determination of Heart Rate and Axis
- Rate = 300 ÷ number of large squares between two R waves
- Or 1500 ÷ number of small squares
- Normal QRS axis = −30° to +90°
- Left axis deviation — LVH, left anterior hemiblock; right axis deviation — RVH, pulmonary embolism
Einthoven’s Triangle and the Cardiac Vector
- The three bipolar limb leads form an equilateral triangle with the heart at its centre
- The heart is regarded as a dipole in a volume conductor
- Cardiac vector — the resultant of all the instantaneous electrical forces in the heart, having magnitude and direction
- A wave is upright when depolarisation moves toward the positive electrode, and inverted when it moves away
- Mean electrical axis is calculated from leads I and aVF, or from the isoelectric lead
Uses of ECG
- Diagnosis of arrhythmias and heart block
- Diagnosis and localisation of myocardial infarction
- Detection of chamber hypertrophy
- Detection of electrolyte disturbances
- Assessing drug effects and toxicity (digitalis, antiarrhythmics)
- Determination of heart rate and electrical axis
Applied Aspects
| Condition | ECG change |
|---|---|
| Acute MI | ST elevation → T inversion → pathological Q waves |
| Myocardial ischaemia | ST depression, T inversion |
| Hyperkalaemia | Tall tented T waves, flat P, wide QRS |
| Hypokalaemia | Flat T, prominent U wave, ST depression |
| Hypocalcaemia | Prolonged QT |
| Hypercalcaemia | Shortened QT |
| Atrial fibrillation | Absent P waves, irregularly irregular RR |
| Complete heart block | P waves independent of QRS |
- The ECG records electrical, not mechanical activity — a normal ECG can occur in a heart that is not pumping (pulseless electrical activity)
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