Q2
LONG ANSWER
10M
★ High-yield
Describe bacterial conjunctivitis with its types and management.
Acute Mucopurulent Conjunctivitis
- The commonest form of bacterial conjunctivitis, and one of the commonest of all ocular conditions. Organisms: staphylococcus aureus (the commonest overall), Streptococcus pneumoniae, haemophilus influenzae (particularly in children, and often with otitis media), and Moraxella
- Symptoms — discomfort and a foreign-body or "sand in the eye" sensation rather than true pain; redness; discharge; and sticking together of the lids on waking, which is characteristic and is often the presenting complaint
- The coloured haloes — patients may describe rainbow haloes around lights, from the prismatic effect of mucus in the tear film. They disappear when the discharge is cleared by blinking or irrigation — the "FICK'S sign" — which distinguishes them from the persistent haloes of angle-closure glaucoma. This is a genuinely useful bedside discrimination
Acute Purulent (hyperacute) Conjunctivitis
- The organism is neisseria gonorrhoeae (and rarely N. Meningitidis). In adults it is transmitted by autoinoculation from the genital tract, and it is an ophthalmic emergency
- Why it is an emergency — because neisseria can penetrate an intact corneal epithelium. Almost every other organism requires a breach; this one does not, so a corneal ulcer and perforation can develop within 24 to 48 hours in an eye that was normal the day before
- Features — explosive onset over hours; copious thick yellow pus, which wells out as soon as the lids are parted and reaccumulates immediately; gross lid oedema such that the lids may be impossible to open; severe chemosis, sometimes with the conjunctiva prolapsing between the lids; a tender preauricular node; and pain
Membranous, Angular and Chronic Forms
| Type | Features and treatment |
|---|---|
| True membranous |
|
| Pseudomembranous |
|
| Angular conjunctivitis |
|
| Chronic bacterial conjunctivitis |
|
Summary of the Bacterial Conjunctivitides
| Type | Organism | Key feature and treatment |
|---|---|---|
| Acute mucopurulent | Staph. Aureus, Strep. Pneumoniae, Haemophilus | Lids stuck on waking; coloured haloes clearing on blinking. Topical broad-spectrum antibiotic; self-limiting |
| Acute purulent (hyperacute) | neisseria gonorrhoeae | Copious pus, gross chemosis, preauricular node; penetrates intact cornea. Systemic ceftriaxone plus hourly irrigation — an emergency |
| Membranous | Corynebacterium diphtheriae | Adherent membrane that bleeds on removal; heals with scarring. Antitoxin and penicillin |
| Pseudomembranous | Adenovirus, streptococci, chemical | Membrane peels without bleeding. Peel and treat the cause |
| Angular | Moraxella lacunata | Maceration at the canthi. Zinc sulphate or tetracycline ointment |
| Chronic | Staphylococcus | Secondary to blepharitis, dacryocystitis or a foreign body — treat the cause |
| Neonatal | Gonococcus, chlamydia, others | Timing indicates the organism; always swab and always treat the parents |
Applied Aspects
- Treat hyperacute purulent conjunctivitis as an emergency with systemic ceftriaxone and hourly irrigation; the cornea can perforate within two days
- Use Fick’s sign to separate haloes; haloes that clear on blinking or irrigation are mucus, and haloes that persist are corneal oedema and may be angle closure
- Never patch a discharging eye, and never give a steroid without knowing the diagnosis; both convert a self-limiting illness into a corneal disaster
- Look for a cause in chronic conjunctivitis — blepharitis, dacryocystitis, a retained foreign body, an ingrowing lash or uncorrected refractive error — since it is a symptom rather than a diagnosis
- Distinguish a true from a pseudo-membrane by whether it bleeds; a bleeding, adherent membrane means diphtheria until proved otherwise and the child needs antitoxin
All questions in Diseases of the Conjunctiva
- Q1Describe the anatomy of the conjunctiva. Classify conjunctivitis and describe the signs used to differentiate its causes. ★
- Q2Describe bacterial conjunctivitis with its types and management. ★
- Q3Describe trachoma with its grading, complications and the SAFE strategy. ★
- Q4Classify allergic conjunctivitis. Describe vernal keratoconjunctivitis and its treatment. ★
- Q5Describe viral conjunctivitis and adult inclusion conjunctivitis. ★
- SN1Describe ophthalmia neonatorum with its causes, treatment and prophylaxis. ★
- SN2Describe pterygium with its aetiology and management. ★
- SN3Describe the degenerative conditions of the conjunctiva and subconjunctival haemorrhage. ★
- SN4Describe xerophthalmia with its WHO classification and management. ★
- SN5Describe symblepharon with its causes, prevention and treatment. ★
- SN6Describe the tumours of the conjunctiva. ★
- SN7Describe conjunctival xerosis and the management of the dry ocular surface.