SN4
SHORT NOTE
5M
★ High-yield
Describe herpes zoster oticus.
Nature and Presentation
Herpes zoster oticus (RAMSAY hunt syndrome) is reactivation of latent varicella-zoster virus in the geniculate ganglion of the facial nerve, producing the triad of otalgia, vesicles in the ear, and lower motor neurone facial palsy.
- The virus lies dormant in the sensory ganglion after chickenpox, and reactivates when cell-mediated immunity declines — with age, immunosuppression, HIV, malignancy, diabetes and stress. Ramsay Hunt in a young patient should prompt HIV testing
- The vesicles appear in the concha, external canal and postauricular skin — the small area of skin supplied by the sensory branch of the facial nerve, which is why this apparently obscure sensory territory matters
Management and Prognosis
- The prognosis IS significantly worse than bell’S palsy, and this is the central clinical fact: complete recovery occurs in only 50 to 60% against some 85 to 90% for Bell’s palsy, and a complete palsy at presentation carries a much worse outlook
- Treatment must begin early — ideally within 72 hours, and the benefit falls off sharply with delay.
- Antiviral — aciclovir 800 mg five times daily, or valaciclovir or famciclovir, for 7 to 10 days; intravenously in severe or immunosuppressed cases
- Corticosteroid — prednisolone 1 mg/kg tapering over 10 to 14 days.
- The combination of antiviral and steroid is standard in Ramsay Hunt, whereas steroid alone suffices in Bell’s palsy
- Analgesia, which is frequently the patient’s main concern, and may require gabapentin, pregabalin or amitriptyline for the neuropathic component
- Eye care IS the urgent priority and must not be left to the patient — lubricant drops by day, ointment and taping at night, a protective shield, and tarsorrhaphy if the cornea is threatened. The risk is greater than in Bell’s palsy.
- Vestibular sedatives for vertigo, used briefly only
- Physiotherapy and facial exercises once recovery begins; and surgical decompression, which is controversial and of unproven benefit
- Follow up with House-Brackmann grading and audiometry
- Complications — post-herpetic neuralgia.
- Prevention — the zoster vaccine reduces the incidence of shingles and of post-herpetic neuralgia in the elderly
- Otalgia precedes the rash, so the patient may present before there is anything visible in the canal
- Eighth nerve involvement distinguishes it from Bell palsy, giving deafness, tinnitus and vertigo alongside the facial weakness
- Recovery is only fifty to sixty per cent, against eighty-five to ninety for Bell palsy.
- Treat within seventy-two hours; the benefit of antiviral therapy falls off sharply after that
All questions in Diseases of the External Ear
- Q1Describe otitis externa with its types, causes and management. ★
- Q2Describe malignant otitis externa. ★
- Q3Describe wax and foreign bodies in the ear with their management. ★
- Q4Describe the tumours of the external ear. ★
- Q5Describe the injuries of the pinna, external canal and tympanic membrane. ★
- SN1Describe otomycosis with its management. ★
- SN2Describe furuncle of the external auditory canal. ★
- SN3Describe perichondritis of the pinna and relapsing polychondritis. ★
- SN4Describe herpes zoster oticus. ★
- SN5Describe keratosis obturans and external canal cholesteatoma. ★
- SN6Describe exostosis and osteoma of the external auditory canal. ★
- SN7Describe myringitis and acquired stenosis of the external canal.